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Persistent coagulopathy in snake bite.

Alka Khadwal1, Bhavneet Bharti, Banani Poddar

  • 1Department of Pediatrics, Government Medical College and Hospital, Chandigarh, India. alkakhadwal@hotmail.com

Indian Journal of Pediatrics
|July 5, 2003
PubMed
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Viper bite bleeding disorders typically resolve within 24 hours. This report details two children experiencing prolonged coagulopathy from snake envenomation, requiring extensive antivenom treatment.

Area of Science:

  • Toxicology
  • Hematology
  • Pediatrics

Background:

  • Viper bite commonly causes bleeding diathesis, usually resolving within 24 hours.
  • Literature on prolonged bleeding disorders post-snake envenomation is limited.
  • Potential causes include decreased antivenin levels or continuous venom release.

Observation:

  • Two pediatric cases of viperine envenomation presented with prolonged coagulopathy.
  • The bleeding disorder persisted for over a week in both children.
  • Significant volumes of antivenom (over 300 ml) were required for correction.

Findings:

  • This case series highlights the possibility of extended coagulopathy following viper bites.
  • The duration and severity of bleeding disorders may exceed typical expectations.

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  • Aggressive and prolonged antivenom therapy might be necessary in complex cases.

    • Implications:

    • Clinicians should consider prolonged coagulopathy in viper bite management.
    • Further research is needed to understand the mechanisms of prolonged bleeding disorders.
    • Revised treatment protocols may be required for severe or persistent envenomation cases.