Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid disease and male reproductive function.

G E Krassas1, P Perros

  • 1Department of Endocrinology and Metabolism, Panagia General Hospital, Thessaloniki, Greece. krassas@the.forthnet.gr

Journal of Endocrinological Investigation
|July 5, 2003
PubMed
Summary

Thyroid disease can affect male fertility, causing sperm abnormalities that often reverse with treatment. While radioiodine therapy may cause temporary issues, severe hypothyroidism can lead to lasting gonadal problems.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration.

Journal of endocrinological investigation·2024
Same author

Health care access of thyroid disease patients in Serbia during the COVID-19 pandemic.

Journal of endocrinological investigation·2022
Same author

[Features of the use of synthetic analogues of thyroid hormones: а 2020 THESIS* questionnaire survey of members of the Belarusian Public Medical Association of Endocrinology and Metabolism].

Problemy endokrinologii·2022
Same author

Use of Thyroid Hormones in Hypothyroid and Euthyroid Patients: A Thesis* Questionnaire Survey of Romanian Physicians *Thesis: Treatment of Hypothyroidism in Europe by Specialists: an International Survey.

Acta endocrinologica (Bucharest, Romania : 2005)·2021
Same author

Use of thyroid hormones in hypothyroid and euthyroid patients: A 2020 THESIS questionnaire survey of members of the Danish Endocrine Society.

Journal of endocrinological investigation·2021
Same author

Antithyroid drugs in Graves' hyperthyroidism: differences between "block and replace" and "titration" regimes in frequency of euthyroidism and Graves' orbitopathy during treatment.

Journal of endocrinological investigation·2020

Area of Science:

  • Endocrinology
  • Reproductive Medicine
  • Thyroidology

Background:

  • Thyroid diseases are common, yet their impact on male reproductive function is understudied.
  • Existing research suggests a link between thyroid dysfunction and male infertility.

Purpose of the Study:

  • To review the effects of hyperthyroidism and hypothyroidism on male reproductive health.
  • To assess the impact of radioiodine therapy on male fertility parameters.

Main Methods:

  • Literature review of studies investigating thyroid disease and male reproduction.
  • Analysis of sperm parameters (count, motility) in relation to thyroid status and treatment.

Main Results:

  • Hyperthyroidism is associated with reversible sperm abnormalities, primarily reduced motility.

Related Experiment Videos

  • Radioiodine therapy can cause transient reductions in sperm count and motility, with minimal permanent risk below 14 MBq.
  • Hypothyroidism's effects are subtler and reversible, but severe, prolonged childhood cases may cause permanent gonadal dysfunction.

    • Conclusions:

    • Thyroid dysfunction significantly impacts male reproductive function, with varying effects depending on the condition and treatment.
    • Prompt management of thyroid disorders is crucial for preserving male fertility.
    • Further research is needed to fully elucidate the mechanisms and long-term consequences.