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High-throughput optimization by statistical designs: example with rat liver slices cryopreservation.

H Martin¹, B Bournique, B Blanchi

¹Drug Safety Evaluation, Aventis Pharma SA, Vitry-sur-Seine, France.

Analytical Biochemistry

|July 5, 2003

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Optimizing cryopreservation for rat liver slices improved reproducibility using specific solutions and incubation times. While biomarker levels remained high, day-to-day variability was reduced, enabling reliable metabolic profiling.

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2026-07-10T14:56:45.297073+00:00

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