Related Experiment Videos
Activity of linezolid against anaerobic bacteria
Josette Behra-Miellet1, Laurent Calvet, Luc Dubreuil
1Faculté de Pharmacie, University of Lille II, 3 rue du Professeur Laguesse, BP83, 59006 Lille cedex, France.
International Journal of Antimicrobial Agents
|July 5, 2003
Abstract:
Minimal inhibition concentrations (MICs) were determined for linezolid (LZD) and compared with those of reference antibiotics against 265 anaerobes. For the Bacteroides fragilis group, MIC range for LZD was 2-4 mg/l. Strains resistant to the other antibiotics were detected including one strain of B. fragilis showing high level resistance to metronidazole (64 mg/l). LZD MIC(50) was 4 mg/l for prevotella and 1 mg/l for fusobacteria. LZD MICs were <1 mg/l for porphyromonas and veillonellae and