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Updated: Sep 23, 2026

Quantitative Polymerase Chain Reaction (qPCR)-Based Rapid Diagnosis of Helicobacter pylori Infection and Antibiotic Resistance
Published on: July 28, 2023
Comparison of genotyping Helicobacter pylori directly from biopsy specimens and genotyping from bacterial cultures
Chang-Young Park1, Minjung Kwak, Oscar Gutierrez
1Department of Medicine, Veterans Affairs Medical Center, and Baylor College of Medicine, Houston, Texas, USA.
Abstract:
PCR for vacA and cagA genotypes of Helicobacter pylori using DNA isolated from infected gastric biopsy specimens was approximately equal to genotyping using bacterial DNA from cultures. Inconsistent results were associated with low H. pylori density in biopsies. A higher proportion of mixed infection was found when biopsies were used.
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