Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Drug-induced chronic urticarias].

P Mathelier-Fusade1

  • 1Centre d'Allergologie, Hôpital Tenon, 4, rue de la Chine, 72020 Paris.

Annales De Dermatologie Et De Venereologie
|July 5, 2003
PubMed
Summary

Drug-induced urticaria, a common allergic reaction, can be acute or chronic. While allergy testing is useful for acute cases, it is often unnecessary for chronic urticaria.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Chronic Urticaria Registry: rationale, methods and initial implementation.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020
Same author

[Omalizumab for the treatment of chronic urticaria: Real-life findings].

Annales de dermatologie et de venereologie·2019
Same author

The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria.

Allergy·2018
Same author

Obesity is not associated with severe chronic urticaria in a French cohort.

Journal of the European Academy of Dermatology and Venereology : JEADV·2017
Same author

Chronic urticaria and hormones: Is there a link?

Journal of the European Academy of Dermatology and Venereology : JEADV·2016
Same author

The definition, diagnostic testing, and management of chronic inducible urticarias - The EAACI/GA(2) LEN/EDF/UNEV consensus recommendations 2016 update and revision.

Allergy·2016

Area of Science:

  • Dermatology
  • Allergology
  • Pharmacology

Context:

  • Urticaria is a frequent drug eruption, often acute and short-lived.
  • Drug-induced urticaria mechanisms vary, including IgE-mediated, immune complex, and non-immunologic pathways.

Purpose:

  • To differentiate the diagnostic utility of allergologic investigations in acute versus chronic drug-induced urticaria.

Summary:

  • Acute urticaria is typically IgE-mediated or triggered by immune complexes or direct mast cell activation, resolving within 6 weeks.
  • Chronic urticaria can be exacerbated by pharmacologic mechanisms (e.g., NSAIDs, aspirin) or angioedema from ACE inhibitors due to bradykinin metabolism.
  • Allergologic investigation is valuable for acute urticaria but generally not indicated for chronic forms.

Impact:

  • Clarifies the limited role of allergy testing in chronic urticaria, guiding clinical practice.
  • Highlights distinct pathomechanisms differentiating acute and chronic drug-induced urticaria.
  • Provides insights into drug-specific triggers for chronic urticaria and angioedema.

Related Experiment Videos