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Related Experiment Videos

Low plasma magnesium in type 2 diabetes.

Monika K Wälti1, Michael B Zimmermann, Giatgen A Spinas

  • 1Laboratory for Human Nutrition, Institute of Food Science and Nutrition, Swiss Federal Institute of Technology, Zurich, Switzerland. monika.waelti@ilw.agrl.ethz.ch

Swiss Medical Weekly
|July 5, 2003
PubMed
Summary

Type 2 diabetes patients in Switzerland often have lower plasma magnesium levels, indicating poor magnesium status. This highlights a common issue impacting diabetic health in the region.

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Area of Science:

  • Endocrinology and Metabolism
  • Nutritional Science

Background:

  • Magnesium depletion negatively affects glucose homeostasis and insulin sensitivity in type 2 diabetes.
  • Low plasma magnesium concentration is a specific indicator of poor magnesium status.
  • Previous studies in the USA and Europe show decreased plasma magnesium in diabetics.

Purpose of the Study:

  • To compare plasma magnesium concentrations between type 2 diabetic patients and healthy controls in Switzerland.

Main Methods:

  • Plasma magnesium concentrations were measured in 109 type 2 diabetic patients.
  • Plasma magnesium concentrations were measured in 156 age- and sex-matched healthy controls.

Main Results:

  • Diabetic patients had significantly lower mean plasma magnesium concentrations (0.77 +/- 0.08 mmol/L) compared to controls (0.83 +/- 0.07 mmol/L).

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  • A higher percentage of diabetic patients (37.6%) had plasma magnesium below the normal reference range compared to controls (10.9%).
  • Plasma magnesium levels did not correlate with glycemic control (HbA1c).

    • Conclusions:

    • Lower plasma magnesium concentrations are prevalent in type 2 diabetic patients in Zurich, Switzerland.
    • Poor magnesium status is common among type 2 diabetics in this Swiss population.