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EST analyses predict the existence of a population of chimeric microRNA precursor-mRNA transcripts expressed in
Genome Biology
|July 8, 2003
Abstract:
A significant population of expressed sequence tags (ESTs) encodes chimeric transcripts containing microRNA (miRNA) precursor sequences as well as pieces of adjacent mRNAs in sense orientation. These chimeric transcripts may potentially be involved in miRNA biosynthesis, and/or affect expression of adjacent mammalian mRNAs.