Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Help available--phenomenological models for research on aging.

Arnold Mitnitski1, Kenneth Rockwood

  • 1Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. Arnold.Mitnitski@Dal.Ca

Science of Aging Knowledge Environment : SAGE KE
|July 8, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interpretable machine learning for high-dimensional trajectories of aging health.

PLoS computational biology·2022
Same author

A quantile frailty index without dichotomization.

Mechanisms of ageing and development·2021
Same author

Response to: 'Correspondence on 'Blood-brain barrier leakage in systemic lupus erythematosus is associated with gray matter loss and cognitive impairment'' by Pamuk and Hasni.

Annals of the rheumatic diseases·2021
Same author

The potential for complex computational models of aging.

Mechanisms of ageing and development·2020
Same author

Generating synthetic aging trajectories with a weighted network model using cross-sectional data.

Scientific reports·2020
Same author

A scoping review of the Clinical Frailty Scale.

BMC geriatrics·2020
Same journal

I come not to bury SAGE KE but to appraise It.

Science of aging knowledge environment : SAGE KE·2006
Same journal

Targeting the role of the endosome in the pathophysiology of Alzheimer's disease: a strategy for treatment.

Science of aging knowledge environment : SAGE KE·2006
Same journal

From bedside to bench: does mental and physical activity promote cognitive vitality in late life?

Science of aging knowledge environment : SAGE KE·2006
Same journal

The unusual genetics of human longevity.

Science of aging knowledge environment : SAGE KE·2006
Same journal

A work in progress: the metabolic syndrome.

Science of aging knowledge environment : SAGE KE·2006
Same journal

WRN's tenth anniversary.

Science of aging knowledge environment : SAGE KE·2006
See all related articles

Scientists can better understand aging by systemizing facts that are not explained in isolation. This approach considers the whole organism and its changes over time for integrative aging research.

Area of Science:

  • Gerontology and Integrative Biology

Background:

  • George Martin's "Help Wanted: Physiologists for Research on Aging" called for better whole-organism aging research.
  • Existing research often analyzes aging factors in isolation.

Purpose of the Study:

  • To propose a novel method for aging research.
  • To encourage consideration of the organism's integrative response over time.

Main Methods:

  • Systematizing scientific facts that lack isolated explanations.
  • Analyzing data holistically to understand organismal aging.

Main Results:

  • The proposed method offers a complementary approach to existing aging research.
  • This systematic approach can reveal new insights into aging processes.

Related Experiment Videos

Conclusions:

  • Integrating isolated facts into a systemic view enhances understanding of aging.
  • This method supports a more comprehensive approach to tackling organismal aging.