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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
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Is DNA cut out for a long life?

David Sinclair1

  • 1Department of Pathology, Harvard Medical School, Boston, MA 02115, USA. David_Sinclair@hms.harvard.edu

Science of Aging Knowledge Environment : SAGE KE
|July 8, 2003
PubMed
Summary

The base excision repair pathway in yeast does not appear to cause aging, despite its role in DNA repair. This study simplifies aging research by using yeast models to investigate DNA damage and its effects.

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