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Updated: Aug 8, 2026

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Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
[The synthesis of a glucosyldiglyceride for constructing pH-sensitive liposomes]
Z Ia Al'shoéĭbi1, T Iu Andriushina, N G Morozova
1Lomonosov State Academy of Fine Chemical Technology, pr. Vernadskogo 86, Moscow, 119571 Russia. httos.mitht@g23.relcom.ru
Bioorganicheskaia Khimiia
|July 9, 2003
Summary
A novel glucosyldiglyceride was synthesized using 11-aminoundecanoic acid. This compound is key for developing pH-sensitive liposomes for targeted drug delivery.
Area of Science:
- Biochemistry
- Organic Chemistry
- Materials Science
Context:
- Liposomes are crucial for drug delivery.
- pH-sensitive liposomes offer targeted release.
- Novel lipid synthesis is essential for advanced formulations.
Purpose:
- To synthesize a novel glucosyldiglyceride.
- To incorporate 11-aminoundecanoic acid residues.
- To create a building block for pH-sensitive liposomes.
Summary:
- A new glucosyldiglyceride was successfully synthesized.
- The synthesis involved 11-aminoundecanoic acid.
- This lipid is designed for pH-sensitive liposome construction.
Impact:
- Enables the development of advanced drug delivery systems.
- Facilitates targeted drug release based on pH.
- Expands the toolkit for liposome formulation research.

