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Published on: October 29, 2014
Echovirus 11 sepsis in a neonate: report of one case
Chien-Chou Hsiao1, Lon-Yen Tsao, Hsiao-Neng Chen
1Department of Pediatrics, Changhua Christian Hospital, No. 135, Nan-Siau Street, Changhua 500, Taiwan.
Insights
Neonatal enterovirus infections, particularly echovirus 11, pose severe risks. This case highlights a fatal outcome in Taiwan due to sepsis-like illness and organ failure despite intensive care.
Area of Science:
- Neonatal infectious diseases
- Virology
- Pediatric critical care
Background:
- Nonpolio enteroviruses are a significant cause of severe illness in neonates.
- Echoviruses and group B coxsackieviruses are the most common culprits in neonatal enterovirus infections.
Observation:
- A case of echovirus 11 infection in a newborn, linked to maternal infection, is presented.
- This represents the first reported fatal case of neonatal enterovirus infection in Taiwan.
Findings:
- The neonate developed severe sepsis-like illness, fulminant hepatitis, and disseminated intravascular coagulation.
- Extensive hemorrhagic manifestations were observed despite comprehensive medical interventions.
Implications:
- This case underscores the critical severity of echovirus 11 infections in neonates.
- Highlights the need for heightened awareness and prompt management of enteroviral infections in newborns.
- Emphasizes the potential for fatal outcomes even with intensive care support.
Abstract:
Neonates infected with nonpolio enteroviruses are at high risk for developing significant illness, including sepsis-like illness, meningoencephalitis, myocarditis and/or hepatitis. Echoviruses and group B coxsackieviruses account for the majority of neonatal enterovirus infections. We reported a case of echovirus 11 infection in newborn associated with maternal infection. To our knowledge, this is the first reported fatal case of neonatal echovirus infection in Taiwan. Eventually, the baby expired because of severe sepsis-like illness, fulminant hepatitis, disseminated intravascular coagulation, and extensive hemorrhagic manifestations in spite of intensive care, intravenous immunoglobulin infusion and exchange transfusion.
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