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[Biodegradable prostatic stents in treating patients with prostatic enlargement]
Urologiia (Moscow, Russia : 1999)
|July 9, 2003
Summary
Biodegradable catheter stents (BCS) offer a safe solution for prostatic hyperplasia (PH) patients with urination issues. These stents degrade naturally, improving urinary flow and quality of life for those unsuitable for surgery.
Area of Science:
- Urology
- Biomaterials Science
Context:
- Prostatic hyperplasia (PH) significantly impacts urination, often necessitating intervention.
- Surgical options like adenomectomy are contraindicated for some PH patients.
- Biodegradable catheter stents (BCS) present an alternative for managing urinary obstruction.
Purpose:
- To evaluate the efficacy and safety of biodegradable catheter stents (BCS) in patients with prostatic hyperplasia (PH).
- To assess BCS as a treatment for urinary disorders caused by urethral compression in PH patients.
- To determine the outcomes of BCS in eliminating suprapubic fistulas in PH patients.
Summary:
- 39 PH patients received BCS, with 19 cases involving suprapubic fistula elimination.
- BCS degraded spontaneously within 4-12 months, with most patients experiencing adequate urination.
- Complications included urethral inflammation and, in two cases, fragment impaction requiring removal.
Impact:
- BCS improved urinary flow (mean Qmax 12.3-10.8 ml/s) and reduced residual urine (32-37 ml) in stented patients.
- The study demonstrates BCS as an effective treatment improving quality of life for PH patients with contraindications to adenomectomy.
- No patient required recystostomy, indicating a favorable safety profile for BCS.