Related Experiment Video
Updated: Sep 23, 2026

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Pemphigus vulgaris mimicking Paget's disease of the breast
Daniel P Guyton1, Kimberly Sloan Stakleff, Eric Regula
1Department of Surgery, Akron General Medical Center, Akron, Ohio 44307, USA. dguyton@agmc.org
Abstract:
We report the development of an ulcerative skin lesion involving the areola of a 37-year-old woman. Clinically the lesion was compatible with Paget's disease, however, histologic evaluation identified pemphigus vulgaris. Differences in the presentation and treatment of these two entities are highlighted. The underlying role of plasminogen activator in the molecular pathology of both diseases is discussed.
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