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Endovascular recanalization of the thrombosed filter-bearing inferior vena cava
Suresh Vedantham1, Thomas M Vesely, Naveen Parti
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Boulevard, Box 8131, St. Louis, Missouri 63110, USA. vedanthams@mir.wustl.edu
Insights
Endovascular methods successfully treated inferior vena cava (IVC) thrombosis in patients with IVC filters, offering a feasible solution for venous occlusions. This approach demonstrated good clinical outcomes and manageable complications.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiovascular Medicine
Background:
- Inferior vena cava (IVC) thrombosis is a serious complication, particularly in patients with IVC filters.
- Treatment options for IVC thrombosis with filters are limited, posing significant clinical challenges.
Purpose of the Study:
- To assess the preliminary experience and efficacy of endovascular techniques for treating IVC thrombosis in patients already possessing IVC filters.
- To evaluate the feasibility and outcomes of minimally invasive procedures in this complex patient group.
Main Methods:
- Ten patients with filter-bearing IVCs experiencing thrombosis and symptomatic limb issues underwent endovascular treatment.
- Procedures included catheter-directed thrombolysis, balloon maceration, mechanical thrombectomy, and stent placement.
- Outcomes monitored included technical and clinical success, complications, filter integrity, and pulmonary embolism (PE) prophylaxis.
Main Results:
- Technical and clinical success rates were 83% and 78%, respectively, across 18 symptomatic limbs.
- One patient (10%) experienced major bleeding (muscular hematoma); no clinically detectable PE occurred during follow-up.
- At a median follow-up of 19 months, limb status varied, with most patients experiencing minimal to no edema.
Conclusions:
- Endovascular recanalization is a feasible and effective treatment for occluded IVCs, even when an IVC filter is present.
- These minimally invasive techniques offer a viable option for managing IVC thrombosis, improving limb symptoms and preventing further complications.
Purpose:
To evaluate the authors' preliminary experience with use of endovascular methods to treat inferior vena cava (IVC) thrombosis in patients with IVC filters.
Materials And Methods:
Catheter-directed thrombolysis, balloon maceration, mechanical thrombectomy, and stent placement were used to treat 10 patients with thrombosis of filter-bearing IVCs causing symptoms in 18 limbs. Procedural challenges, technical and clinical success, complications, postprocedural filter status, and postprocedural pulmonary embolism (PE) prophylaxis were monitored.
Results:
Technical and clinical success were achieved in 15 of 18 (83%) and 14 of 18 symptomatic limbs (78%), respectively. Major bleeding (muscular hematoma) occurred in one patient (10%). Postprocedural PE prophylaxis included anticoagulation (n = 8) and placement of a new filter into a newly placed Wallstent (n = 1). During clinical follow-up, no clinically detectable PE was observed. Data pertaining to late limb status were available at a median of 19 months (range 1-46 months) follow-up in seven patients: three patients were asymptomatic, two patients had ambulatory edema only, one patient had constant mild edema, and one patient had constant severe edema. Postprocedural filter stability was radiographically documented at a median of 255 days (range, 4-1021 d) of follow-up.
Conclusion:
Endovascular recanalization of the occluded IVC is feasible even in the presence of an IVC filter.
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