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["In vitro" susceptibility of group A beta-haemolytic streptococcus]
S Noviello1, F Ianniello, S Esposito
1Clinica Malattie Infettive Seconda Università degli Studi di Napoli.
Insights
Streptococcus pyogenes caused over 30% of pediatric acute pharyngo tonsillitis cases. While no resistance to beta-lactams was found, high erythromycin resistance in Streptococcus pyogenes necessitates ongoing surveillance.
Area of Science:
- Pediatric Infectious Diseases
- Bacteriology
- Epidemiology
Context:
- Acute pharyngo tonsillitis is a common pediatric illness.
- Streptococcal infections are a significant concern in children.
- Understanding bacterial etiology and resistance patterns is crucial for effective treatment.
Purpose:
- To determine the incidence of streptococcal etiology in pediatric acute pharyngo tonsillitis.
- To assess the in vitro susceptibility of Group A beta-hemolytic Streptococcus (S. pyogenes) isolates.
- To inform public health strategies regarding antibiotic resistance.
Summary:
- An epidemiological survey of 827 pediatric patients from March 1995 to November 1996 identified Streptococcus pyogenes as the cause in 32.7% of acute pharyngo tonsillitis cases.
- In vitro testing revealed no resistance to beta-lactam antibiotics among the S. pyogenes isolates.
- A high rate of resistance (38.7%) to erythromycin was observed in the bacterial isolates.
Impact:
- Highlights the prevalence of S. pyogenes in pediatric pharyngo tonsillitis.
- Identifies a significant emerging resistance to erythromycin, impacting treatment options.
- Underscores the need for continuous epidemiological surveillance of S. pyogenes antibiotic resistance in the community.
Abstract:
An epidemiological survey on 827 pediatric patients has been performed from March '95 to November '96 to verify the incidence of streptococcal etiology during acute pharyngo tonsillitis in pediatric age and the "in vitro" susceptibility of the group A beta hemolytic Streptococcus isolates. S. pyogenes was responsible of acute pharyngo tonsillitis in 32.7% of cases. No strain was resistant to beta lactams, but resistance to erythromycin was high (38.7% of bacterial isolates). These results suggest the importance of a constant epidemiological surveillance of bacterial resistance of S. pyogenes in the community setting.