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Updated: Sep 23, 2026

Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model
Published on: February 10, 2023
Intrapericardial chemotherapy for the management of neoplastic cardiac tamponade
Neelam Siddiqui1, Abdulrahman I Al-Diab
1Department of Medicine, College of Medicine, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia. neelamsiddiqui@hotmail.com
Abstract:
A young patient with disseminated osteogenic sarcoma presented with cardiac tamponade. She was successfully managed with pericardiocentesis and intrapericardial instillation of cisplatin. There was no reaccumulation of pericardial fluid or recurrence of tamponade until the patient's death 12 months later. Intrapericardial chemotherapy may be effective in the management of cardiac tamponade secondary to malignancy.
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