Related Experiment Videos
Comparison of lutein bioavailability from vegetables and supplement
Patrizia Riso1, Antonella Brusamolino, Salvatore Ciappellano
1Department of Food Science and Technology and Microbiology, Division of Human Nutrition-University of Milan, Milan, Italy. patrizia.riso@unimi.it
Summary
This study compared lutein bioavailability from spinach, broccoli, and a supplement. The supplement (VEGEX) and spinach showed the highest and longest-lasting lutein plasma concentrations in healthy women.
Area of Science:
- Nutrition Science
- Biochemistry
- Human Health
Background:
- Lutein, a carotenoid found in leafy greens, is linked to preventing oxidative stress-related diseases.
- Understanding lutein bioavailability is crucial for dietary recommendations and health interventions.
Purpose of the Study:
- To compare the bioavailability of lutein from spinach, broccoli, and an oil-based supplement (VEGEX).
- To assess the plasma lutein response over time following single-dose intake from different sources.
Main Methods:
- Eight healthy females consumed controlled low-carotenoid diets.
- Lutein sources (spinach, broccoli, VEGEX) with olive oil and bread were administered on separate occasions.
- Plasma lutein concentrations were measured at multiple time points up to 104 hours.
Main Results:
- Lutein plasma levels significantly increased 6-12 hours post-ingestion, peaking at 10-12 hours.
- The highest lutein concentrations were observed after consuming the VEGEX supplement.
- Elevated lutein levels were sustained for up to 80 hours with VEGEX and spinach intake.
Conclusions:
- Single-dose lutein intake from various food sources and supplements significantly impacts plasma lutein levels in the short term.
- The VEGEX supplement and spinach demonstrated superior bioavailability and sustained elevation of plasma lutein.