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Appropriateness of choice and interpretation of tests for thrombophilic defects: a practical experience
1Servizio di Medicina di Laboratorio, Azienda Ospedaliera di Padova, Via Giustiniani 2, 35.100 Padua, Italy. pcarraro@hotmail.com
Background:
The use of laboratory coagulation tests in some fields of primary medicine is not well defined in available guidelines. In Italy, general practitioners tend to lack a thorough understanding of the utility of knowledge of coagulation inhibitors.
Methods:
We reviewed the clinical conditions for which outpatients have been referred to our laboratory for antithrombin testing or for inherited thrombophilia tests panels over a 3-week period. Evidence-based guidelines were used to identify the appropriate requests.
Results:
Numerous unnecessary tests were requested for both antithrombin and thrombophilia, particularly in obstetric and gynaecological situations in the setting of hormonal contraceptive treatment.
Conclusions:
Laboratory specialists must improve upon their communication with physicians in order to achieve an appropriate use of coagulation tests.