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Updated: Sep 23, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Biologic therapy for psoriasis--the first wave: infliximab, etanercept, efalizumab, and alefacept

Jeffrey M Weinberg1, Ritu Saini, William D Tutrone

  • 1Department of Dermatology, St. Luke's-Roosevelt Hospital Center, Beth Israel Medical Center, New York, New York, USA. jmw27@columbia.edu

Journal of Drugs in Dermatology : JDD
|July 11, 2003
PubMed

Over the last several years, a new generation of therapies for psoriasis has been in development. These biologic therapies target the activity of T lymphocytes and cytokines responsible for the inflammatory nature of this disease. In this review, we present an update on the progress of the four biologic agents in the forefront: infliximab, etanercept, efalizumab, and alefacept. The mechanism of each drug will be reviewed, as well as the most recent efficacy and safety data.

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