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[Epithelioid vascular tumor]
Vesna Skuletić1, Radojka Bokun, Zeljka Tatomirović
1Vojnomedicinska akademija, ZPSM-Institut za patologiju, Beograd. vesnaskul@yahoo.com
Vojnosanitetski Pregled
|July 11, 2003
Summary
This case report details an unusual epithelioid vascular tumor in the upper vena cava. The tumor, diagnosed as intravascular, solid, epithelioid hemangioma, presented with thrombotic complications.
Area of Science:
- Vascular Oncology
- Pathology
- Tumor Biology
Background:
- Epithelioid vascular tumors are neoplasms of endothelial cells with variable morphology and biological potential.
- These tumors can range from benign to malignant forms.
- Understanding their diverse presentations is crucial for diagnosis and management.
Observation:
- A case of epithelioid vascular tumor in the upper vena cava is presented.
- The tumor exhibited solid growth with attempts at forming vascular channels.
- Clinical manifestation included thrombotic complications.
Findings:
- Immunophenotype indicated endothelial cells with low proliferative potential and intracellular lumina formation.
- Histological and histochemical analyses led to the diagnosis of intravascular, solid, epithelioid hemangioma.
- Distinguishing features from epithelioid hemangioendothelioma included benign cytomorphology, absence of pathological mitoses, prominent inflammatory infiltrate with eosinophilia, and presence of pericytes.
Implications:
- This case highlights an immunophenotypically interesting variant of epithelioid vascular tumors.
- Accurate diagnosis is essential, differentiating it from more aggressive neoplasms like epithelioid hemangioendothelioma.
- The presence of pericytes may contribute to better tumor growth control.