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[Hypersensitivity reactions to cancer chemotherapeutic agents]
Atsushi Sato1, Akiko Sakashita, Susumu Taguchi
1Department of Internal Medicine, Showa University Northern Yokohama Hospital, 35-1 Chigasaki-cho, Tsuzuki-ku, Yokohama, Kanagawa 224-8503, Japan.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|July 11, 2003
Abstract:
Although hypersensitivity reactions to the anticancer drug are rare, since the reactions occasionally are clinical problems enough, that measure is important. The backgrounds (the etiologic mechanisms, the frequency, and etc) differ by each, therefore the knowledge for each medicine is required for measures including prediction and the prevention. This paper reviews the sensitivity reactions of various anticancer drugs (especially, paclitaxel, cisplatin and carboplatin) also including the molecular targeting drugs (trastuzumab, rituximab).