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Updated: Aug 2, 2026

The Use of Chemostats in Microbial Systems Biology
Published on: October 14, 2013
[Deterministic differential equations in cytokinetics]
1Service de mathématiques appliquées, institut d'électricité Montefiore (B28), université de Liège, 4000 Liège, Belgique. fourre@montefiore.ulg.ac.be
Abstract:
Carcinogenesis is generally viewed as the result of a disrupted equilibrium between the processes of proliferation, differentiation, migration and loss. In cell kinetics, perturbation of fundamental kinetic parameters such as the mitotic index or the growth fraction may reflect a carcinogenic process. In this paper, we present a system of deterministic differential equations describing the dynamical evolution of a cell population. We show that this model can account for asynchronicity of cells and simulate the fraction of labelled mitoses experiment as well.
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