Related Experiment Videos
MHC class II determinants on peripheral blood monocytes from newly diagnosed IDDM patients
A Pituch-Noworolska1, H Dziatkowiak, M Zembala
1Department of Clinical Immunology, Polish-American Childrens Hospital, Karków.
Endokrynologia Polska
|January 1, 1991
Abstract:
The expression of MHC class II determinants (HLA-DR, HLA-DP and Ia7) on peripheral blood monocytes (OKM1+ cells) was studied in 20 children with newly diagnosed IDDM. Monocytes of 10 children with IDDM and familial predisposition showed a statistically significant increase of HLA-DR expression when compared to control group (10 healthy children). There were no significant differences concerning Ia7 expression. HLA-DP expression was similar in all studied groups.