Related Experiment Videos

Pars planitis in the Mexican Mestizo population: ocular findings, treatment, and visual outcome

Lourdes Arellanes-García1, Luz Navarro-López, Claudia Recillas-Gispert

  • 1Inflammatory Eye Disease Clinic, 'Dr Luis Sánchez Bulnes Hospital', Asociación Para Evitar la Ceguera en México, San Lucas Coyoacán, Mexico. agml@servidor.unam.mx

Abstract

Insights

Classic pars planitis (CPP) in Mexican males often presents bilaterally before age 14, with decreased vision being the main symptom. Vitreous and retinal findings, along with cataract and cystoid macular edema, are common.

Area of Science:

  • Ophthalmology
  • Immunology

Background:

  • Classic pars planitis (CPP) is an inflammatory eye condition.
  • Understanding its clinical profile in diverse populations is crucial for effective management.

Purpose of the Study:

  • To delineate the clinical manifestations, complications, and treatment outcomes of CPP in Mexican patients.
  • To identify demographic and clinical patterns specific to this population.

Main Methods:

  • A retrospective descriptive case series.
  • Analysis of clinical features, complications, and treatments of 160 CPP patients over a decade (1990-1999).

Main Results:

  • CPP predominantly affected males, with a mean age of 10 years; 84.4% had bilateral involvement.
  • Common manifestations included vitritis, snowballs, retinal vasculitis, and snowbanks.
  • Cystoid macular edema (63.4%) and cataract (47.5%) were the most frequent complications, with mean final visual acuity of 20/30.

Conclusions:

  • CPP in Mexico is characterized by early onset (under 14), male predominance, and bilateral presentation.
  • Vitreous and retinal involvement are key features, with cataract and CME being significant complications.
  • Treatment primarily involves periocular/systemic corticosteroids and other immunosuppressants.

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...