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Updated: Sep 23, 2026
In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
[Utility of laser photocoagulation of choroidal neovascularization in angioid streaks]
Miho Haruyama1, Mitsuko Yuzawa
1Department of Ophthalmology, Surugadai Hospital, Nihon University, 1-8-13 Surugadai, Kanda, Chiyoda-ku, Tokyo 101-8309, Japan.
Purpose:
We evaluate the utility of laser photocoagulation of extrafoveal choroidal neovascularization (CNV) in angioid streaks.
Subjects And Methods:
Eleven eyes of 10 patients with extrafoveal CNV secondary to angioid streaks that underwent direct laser photocoagulation were followed for 5 months or more. We performed an intense laser photocoagulation of a CNV area determined by fluorescein angiography. We evaluated CNV diameter, the shortest distance between CNV and the fovea, the best visual acuity, the final visual acuity, existence, period, and region of the recurrence, and changes in fundus findings.
Result:
The logarithm of the minimum angle of resolution (log MAR) final visual acuity in 9 eyes deteriorated more than two levels. The recurrence of CNV was observed in 11 eyes, in 9 eyes CNV expanded and involved the fovea, and in two eyes photocoagulation was performed but caused an atrophic creep and resulted in scar formation including the fovea.
Conclusion:
Based on these results, laser photocoagulation is not a good therapy for CNV in angioid streaks.