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Extramedullary liver plasmacytoma a rare presentation.

Maria Teresa Petrucci1, Maria Cristina Tirindelli, Marianna De Muro

  • 1Ematologia, Dipartimento di Biotecnologie Cellulari ed Ematologia, Università La Sapienza, Roma, Italy. marter@bce.med.uniroma1.it

Leukemia & Lymphoma
|July 12, 2003
PubMed
Summary

We present a rare case of liver plasmacytoma, a solitary tumor without systemic disease. This unusual hepatic lesion achieved good remission with melphalan and prednisone treatment over five years.

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Area of Science:

  • Oncology
  • Hepatology
  • Hematology

Background:

  • Solitary plasmacytoma is rare, with liver involvement often indicating aggressive multiple myeloma.
  • Plasma cell infiltration in the liver typically signifies advanced systemic disease.

Observation:

  • An unusual case of liver plasmacytoma was diagnosed in a patient without evidence of systemic disease.
  • Diagnosis was confirmed via percutaneous needle biopsy of the hepatic lesion.

Findings:

  • The patient received six courses of melphalan and prednisone chemotherapy.
  • A good clinical remission was achieved and maintained for five years post-treatment.

Implications:

  • This case highlights the possibility of localized liver plasmacytoma as a distinct entity.

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  • Successful treatment with chemotherapy suggests a viable therapeutic strategy for this rare condition.