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[Neurological involvement in systemic sclerosis].

I Campello Morer1, J Velilla Marco, J L Hortells Aznar

  • 1Unidad de Neurología. Fundación Hospital Manacor. Baleares. Spain. isacam@saludalia.com

Revista Clinica Espanola
|July 12, 2003
PubMed
Summary
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Neurological complications are more common in systemic sclerosis (SS) than previously thought. This study found central nervous system involvement in 26.9% and peripheral neuropathy in 39.1% of patients.

Area of Science:

  • Neurology
  • Rheumatology
  • Autoimmune Diseases

Context:

  • Systemic sclerosis (SS) is a connective tissue disease.
  • Neurological complications in SS are often underestimated.
  • Recent studies suggest a higher prevalence of neurological involvement in SS.

Purpose:

  • To determine the prevalence of central nervous system (CNS) pathology and peripheral neuropathy in SS patients.
  • To characterize the neurological manifestations in SS.
  • To explore associations between neurological involvement and clinical/autoimmune parameters.

Summary:

  • Clinical neurological examination and electroneurograms were performed on 26 SS patients.
  • CNS involvement was observed in 26.9% of patients, with headache and neuropsychiatric issues being most common.

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  • Peripheral neuropathy affected 39.1% of patients, predominantly as axonal polyneuropathy.

    • Impact:

    • Highlights the significant prevalence of neurological complications in systemic sclerosis.
    • Provides data on the types and characteristics of neurological involvement in SS.
    • Informs clinical practice and future research on managing neurological aspects of SS.