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Related Experiment Videos

400000 nematode ESTs on the Net.

John Parkinson1, Makedonka Mitreva, Neil Hall

  • 1Institute of Cell, Animal and Population Biology, Ashworth Laboratories, King's Buildings, West Mains Rd, University of Edinburgh, EH9 3JT, Edinburgh, UK. john.parkinson@ed.ac.uk <john.parkinson@ed.ac.uk>

Trends in Parasitology
|July 12, 2003
PubMed
Summary

The parasitic nematode expressed sequence tag (EST) project is generating vital genomic data for over 30 nematode species. This initiative provides extensive EST data and develops database tools for wider accessibility.

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Area of Science:

  • Parasitology
  • Genomics
  • Bioinformatics

Background:

  • Nematode parasites pose significant threats to agriculture and human health.
  • Understanding nematode genomes is crucial for developing control strategies.
  • Large-scale sequencing projects are essential for advancing genomic research.

Purpose of the Study:

  • To provide an update on the status of the parasitic nematode expressed sequence tag (EST) project.
  • To describe the database tools developed for disseminating nematode EST data.
  • To highlight the collaborative effort in generating and sharing genomic information.

Main Methods:

  • Generation of expressed sequence tags (ESTs) from >30 nematode species.
  • Large-scale sequencing and data generation exceeding 400,000 ESTs.

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  • Development of database tools for data dissemination and accessibility.

    • Main Results:

    • Over 400,000 nematode ESTs are currently available.
    • A further 130,000 ESTs are planned for future release.
    • Database tools are being developed to facilitate access to this valuable data.

    Conclusions:

    • The parasitic nematode EST project is a major contributor to nematode genomics.
    • The project significantly expands the available genomic resources for nematode research.
    • Developed database tools will enhance the utility and accessibility of nematode genomic data for the scientific community.