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Pattern recognition molecules and innate immunity to parasites
David H McGuinness1, Prabhjyot K Dehal, Richard J Pleass
1Department of Molecular & Cellular Pathology, University of Dundee Medical School, Ninewells Hospital, DD1 9SY, Dundee, UK.
Trends in Parasitology
|July 12, 2003
Abstract:
Recent pioneering advances in understanding how plants, insects and worms eliminate pathogens has led to the realization that innate immunity plays a vital role in protecting humans from infection. This comprehensive review examines the molecules involved in innate immune responses, how they act to control parasites and if their engagement can explain many immune features characteristic of parasitic infections.