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Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

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The discovery net system for high throughput bioinformatics.

Anthony Rowe¹, Dimitrios Kalaitzopoulos, Michelle Osmond

¹Department of Computing Imperial College, 180 Queens Gate, London, SW7 2RH, UK. asr99@doc.ic.ac.uk

Bioinformatics (Oxford, England)

|July 12, 2003

Summary

This summary is machine-generated.

Discovery Net middleware enables bioinformatics applications by integrating Grid standards and web services. This facilitates the creation of reusable workflows for genome annotation and protein analysis.

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Area of Science:

Bioinformatics
Computational Biology
Grid Computing

Background:

High-performance bioinformatics applications necessitate Grid technologies and protocols.
Developers need to abstract away low-level Grid component complexities.

Purpose of the Study:

To present the Discovery Net system as a middleware solution for bioinformatics.
To demonstrate the creation of reusable workflows and Grid-based applications.

Main Methods:

Developed the Discovery Net middleware for integrating bioinformatics tools.
Utilized Grid standards, including web services, for tool integration.
Composed reusable workflows from integrated services for specific bioinformatics tasks.

Main Results:

The Discovery Net system successfully integrates diverse bioinformatics tools.
Created a Grid-based application for Genome Annotation.
Developed specific workflows for nucleotide annotation, protein annotation, and metabolic profile text analysis.

Conclusions:

The Discovery Net system simplifies the development of high-performance bioinformatics applications.
Enables the creation and deployment of reusable, service-oriented workflows.
Facilitates advanced genomic and proteomic data analysis through Grid-based solutions.