Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vision01:24

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Visual Agnosia01:12

Visual Agnosia

Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round end"...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accurate and Rapid Electrochemical Detection of Fentanyl in Hydrophobic Ionic Liquid at Subzero Temperatures.

Electrochimica acta·2025
Same author

Effectiveness of non-pharmaceutical interventions as implemented in the UK during the COVID-19 pandemic: a rapid review.

Journal of public health (Oxford, England)·2025
Same author

Canadian Surgery Forum: Abstracts of presentations to the Annual Meetings of the Canadian Association of Bariatric Physicians and Surgeons, Canadian Association of General Surgeons, Canadian Association of Thoracic Surgeons, Canadian Hepato-Pancreato-Biliary Association, Canadian Society of Surgical Oncology, Canadian Society of Colon and Rectal Surgeons, Vancouver, BC, Sept. 17-21, 2013.

Canadian journal of surgery. Journal canadien de chirurgie·2025
Same author

OSAIRIS: Lessons Learned From the Hospital-Based Implementation and Evaluation of an Open-Source Deep-Learning Model for Radiotherapy Image Segmentation.

Clinical oncology (Royal College of Radiologists (Great Britain))·2024
Same author

Non-pharmaceutical interventions to reduce COVID-19 transmission in the UK: a rapid mapping review and interactive evidence gap map.

Journal of public health (Oxford, England)·2024
Same author

Durvalumab with or without tremelimumab versus the EXTREME regimen as first-line treatment for recurrent or metastatic squamous cell carcinoma of the head and neck: KESTREL, a randomized, open-label, phase III study.

Annals of oncology : official journal of the European Society for Medical Oncology·2022

Related Experiment Video

Updated: Jul 11, 2026

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
13:12

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells

Published on: October 15, 2017

Visual function following neurosurgical optic nerve decompression for compressive optic neuropathy.

T J Sleep1, P R Hodgkins, S Honeybul

  • 1Department of Ophthalmology, Southampton General Hospital, Southampton, UK. tamsinsleep@doctors.org.uk

Eye (London, England)
|July 12, 2003
PubMed
Summary
This summary is machine-generated.

Neurosurgical decompression of the optic nerve can improve or maintain visual acuity in many patients with intracranial tumors. Some patients experience late improvements, while others may see a decline in vision post-surgery.

More Related Videos

Minimally Invasive Surgical Decompression of Occipital Nerves
04:06

Minimally Invasive Surgical Decompression of Occipital Nerves

Published on: September 13, 2024

A Surgical Approach for Optic Nerve Crush in a Rabbit Model
06:15

A Surgical Approach for Optic Nerve Crush in a Rabbit Model

Published on: July 8, 2025

Related Experiment Videos

Last Updated: Jul 11, 2026

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
13:12

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells

Published on: October 15, 2017

Minimally Invasive Surgical Decompression of Occipital Nerves
04:06

Minimally Invasive Surgical Decompression of Occipital Nerves

Published on: September 13, 2024

A Surgical Approach for Optic Nerve Crush in a Rabbit Model
06:15

A Surgical Approach for Optic Nerve Crush in a Rabbit Model

Published on: July 8, 2025

Area of Science:

  • Neurosurgery
  • Ophthalmology
  • Neuro-oncology

Background:

  • Intracranial tumors can compress the optic nerve, leading to visual impairment.
  • Neurosurgical decompression aims to relieve this pressure and preserve visual function.

Purpose of the Study:

  • To evaluate visual function outcomes after optic nerve decompression during intracranial tumor resection.
  • To provide data for patient counseling regarding visual prognosis.

Main Methods:

  • Retrospective review of 27 patients (36 optic nerves) undergoing neurosurgical decompression.
  • Analysis of visual acuity and visual fields in patients with sphenoid wing meningioma and other intracranial tumors.

Main Results:

  • 47% of decompressed eyes showed improved visual acuity; 20% had worse acuity at follow-up (1-97 months).
  • Improvement was immediate in two-thirds of eyes with better acuity; late improvement occurred in one-third.
  • 33% of eyes achieved preoperative acuity levels; 6% improved to this level postoperatively.

Conclusions:

  • Most eyes maintained or improved acuity following optic nerve decompression.
  • Visual function can continue to improve post-surgery, but some eyes may deteriorate.
  • No correlation found between preoperative symptom duration or acuity level and postoperative visual change.