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Updated: Aug 5, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Reference values for change in body mass index from birth to 18 years of age
J Karlberg1, C W Kwan, K Albertsson-Wikland
1Clinical Trials Centre, The University of Hong Kong, Hong Kong SAR, PR China. jpekarl@hkucc.hku.hk
Insights
New reference values track changes in Body Mass Index (BMI) for children. These growth rate values aid in evaluating nutritional and therapeutic interventions for pediatric health.
Area of Science:
- Pediatric Endocrinology
- Nutritional Science
- Biostatistics
Background:
- Body Mass Index (BMI) is crucial for assessing pediatric nutritional status.
- Existing cross-sectional BMI references lack longitudinal change evaluation.
- Accurate assessment of childhood nutritional interventions requires BMI change reference values.
Purpose of the Study:
- To present novel reference values for Body Mass Index (BMI) change in children.
- To provide tools for evaluating the effectiveness of pediatric interventions.
- To support clinical decision-making in pediatric nutrition.
Main Methods:
- Utilized longitudinal data from 3650 healthy, full-term Swedish children.
- Calculated reference values for BMI change as standard deviation scores.
- Developed mathematical functions adjusting for gender, age, and measurement intervals (0.25-5 years).
Main Results:
- Presented reference values for BMI change in healthy children from birth to 18 years.
- Demonstrated the utility of these values via a clinical computer program graph.
- Enabled computation and visualization of individual child's predicted BMI change range (-2 to +2 SD).
Conclusions:
- Introduced the first BMI growth rate values for research and clinical use.
- These values facilitate the evaluation of nutritional, surgical, and therapeutic interventions.
- Provides enhanced support for clinical decision-making in pediatric care.
Unlabelled:
Body mass index (BMI) has become the measure of choice for determination of nutritional status during the paediatric years, as in adults. Recently, several cross-sectional BMI childhood reference values standards have been published. In order precisely to evaluate childhood nutritional interventions, reference values allowing for the evaluation of changes in BMI values are also needed. For the first time, such reference values can be presented based on 3650 longitudinally followed healthy Swedish children born full term. The reference values for the change in BMI are given as the change in BMI standard deviation scores. The reference values are given as means of mathematical functions adjusting for gender, age of the child and the length of the interval between two measurements for interval lengths of 0.25 to 1.0 y before 2 y of age and of 1 to 5 y between birth and 18 y. The usefulness of the reference values is proved by a graph that forms a part of a clinical computer program; the -2 to +2 standard deviation range of the predicted change in BMI can be computed for an individual child and drawn in the graph as an extended support for clinical decision-making.
Conclusion:
For the first time this communication gives access to BMI growth rate values that can be used both in research and in the clinic to evaluate various interventions, be they nutritional, surgical or therapeutic.
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