Reference values for change in body mass index from birth to 18 years of age

J Karlberg1, C W Kwan, K Albertsson-Wikland

  • 1Clinical Trials Centre, The University of Hong Kong, Hong Kong SAR, PR China. jpekarl@hkucc.hku.hk

Insights

New reference values track changes in Body Mass Index (BMI) for children. These growth rate values aid in evaluating nutritional and therapeutic interventions for pediatric health.

Area of Science:

  • Pediatric Endocrinology
  • Nutritional Science
  • Biostatistics

Background:

  • Body Mass Index (BMI) is crucial for assessing pediatric nutritional status.
  • Existing cross-sectional BMI references lack longitudinal change evaluation.
  • Accurate assessment of childhood nutritional interventions requires BMI change reference values.

Purpose of the Study:

  • To present novel reference values for Body Mass Index (BMI) change in children.
  • To provide tools for evaluating the effectiveness of pediatric interventions.
  • To support clinical decision-making in pediatric nutrition.

Main Methods:

  • Utilized longitudinal data from 3650 healthy, full-term Swedish children.
  • Calculated reference values for BMI change as standard deviation scores.
  • Developed mathematical functions adjusting for gender, age, and measurement intervals (0.25-5 years).

Main Results:

  • Presented reference values for BMI change in healthy children from birth to 18 years.
  • Demonstrated the utility of these values via a clinical computer program graph.
  • Enabled computation and visualization of individual child's predicted BMI change range (-2 to +2 SD).

Conclusions:

  • Introduced the first BMI growth rate values for research and clinical use.
  • These values facilitate the evaluation of nutritional, surgical, and therapeutic interventions.
  • Provides enhanced support for clinical decision-making in pediatric care.
Abstract

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