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Related Experiment Videos

Use of a self-designed bladder controller for restoring bladder function in paraplegic dogs.

Shi-bo Wang1, Chun-lin Hou, Ying-min Diao

  • 1Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China. Wangshibo118@hotmail.com

Chinese Journal of Traumatology = Zhonghua Chuang Shang Za Zhi
|July 15, 2003
PubMed
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A self-designed bladder controller successfully restored micturition in paraplegic dogs. This device, combined with sacral deafferentation, enabled controlled voiding by regulating bladder and intraurethral pressures.

Area of Science:

  • Neuroscience
  • Veterinary Medicine
  • Biomedical Engineering

Background:

  • Paraplegic dogs exhibit impaired micturition due to spinal cord transection.
  • Restoring bladder function is crucial for animal welfare and research models.

Purpose of the Study:

  • To evaluate a self-designed bladder controller for restoring micturition in paraplegic dogs.
  • To assess the efficacy of sacral deafferentation combined with electrical stimulation.

Main Methods:

  • Spinal cord transection and bilateral S2 electrode implantation were performed in four dogs.
  • Sacral dorsal rhizotomy (S1-3) was employed, followed by daily electrical stimulation.
  • Urodynamic testing and vesicography were utilized to assess bladder function.

Related Experiment Videos

Main Results:

  • All dogs achieved controlled micturition via electrical stimulation, voiding 80-140 ml per instance.
  • Vesicography confirmed adequate bladder filling and bladder neck opening during stimulation.
  • Urodynamic data indicated micturition occurred when bladder pressure exceeded intraurethral pressure.

Conclusions:

  • The developed bladder controller, alongside sacral deafferentation, effectively restored micturition function in paraplegic dogs.
  • This approach offers a potential solution for managing bladder dysfunction in spinal cord-injured animals.