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Structural and evolutionary analysis of an orangutan foamy virus
Ernst J Verschoor1, Susan Langenhuijzen, Saskia van den Engel
1Department of Virology, Biomedical Primate Research Centre, Rijswijk, The Netherlands. verschoor@bprc.nl
Journal of Virology
|July 15, 2003
Abstract:
The full-length proviral genome of a foamy virus infecting a Bornean orangutan was amplified, and its sequence was analyzed. Although the genome showed a clear resemblance to other published foamy virus genomes from apes and monkeys, phylogenetic analysis revealed that simian foamy virus SFVora was evolutionarily equidistant from foamy viruses from other hominoids and from those from Old World monkeys. This finding suggests an independent evolution within its host over a long period of time.