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The comorbidity of migraine
Nancy C P Low1, Kathleen Ries Merikangas
1Mood and Anxiety Disorders Program of the Intramural Research Program at the National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services in Bethesda, Maryland MD 20892-2670, USA.
CNS Spectrums
|July 15, 2003
Summary
Migraine is frequently linked with other medical issues like stroke and asthma, and mental health conditions such as mood and anxiety disorders. Understanding these comorbidities is crucial for comprehensive migraine care.
Area of Science:
- Neurology
- Psychiatry
- Epidemiology
Background:
- Migraine is a complex neurological disorder with significant comorbidity.
- Numerous medical and psychiatric conditions are associated with migraine, impacting patient health and treatment.
- Existing literature on migraine comorbidity is extensive, necessitating focused reviews.
Purpose of the Study:
- To review methodologic issues in studying migraine comorbidity.
- To provide an overview of medical and psychiatric conditions commonly associated with migraine.
- To highlight key comorbidities based on community and case-control studies.
Main Methods:
- Literature review focusing on community and case-control studies.
- Analysis of associations between migraine and various medical systems (cardiovascular, respiratory, neurologic, gastrointestinal, immunologic).
- Examination of links between migraine and psychiatric disorders.
Main Results:
- Strong associations found between migraine and stroke, asthma, and allergies.
- Migraine shows significant comorbidity with mood and anxiety disorders in the general population.
- Specific methodologic challenges in comorbidity research were addressed.
Conclusions:
- Migraine comorbidity is a significant clinical issue.
- Stroke, asthma, allergies, mood disorders, and anxiety disorders are key associated conditions.
- Further research is needed to understand the mechanisms underlying migraine comorbidity.