Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

NSAIDs: maternal and fetal considerations.

A Schoenfeld1, Y Bar, P Merlob

  • 1Department of Obstetrics & Gynecology, Beilinson Medical Center, Petabh-Tiqva, Israel.

American Journal of Reproductive Immunology (New York, N.Y. : 1989)
|October 1, 1992
PubMed
Summary

Low-dose aspirin use in pregnancy may reduce preeclampsia and fetal growth issues. This review examines aspirin

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DNA methyltransferase 3A (DNMT3A) mutations and PD-(L)1 blockade efficacy in non-small-cell lung cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2025
Same author

Effectiveness of a Meta-Cognitive Group Intervention for Older Adults with Subjective Cognitive Decline or Mild Cognitive Impairment: The ASPIRE Randomized Controlled Trial.

The journal of prevention of Alzheimer's disease·2024
Same author

Variation in expenditure for common, high cost surgical procedures in a working age population: implications for reimbursement reform.

BMC health services research·2019
Same author

Reduction in exposure to arsenic from drinking well-water in Bangladesh limited by insufficient testing and awareness.

Journal of water, sanitation, and hygiene for development : a journal of the International Water Association·2017
Same author

On the relationship between pregnancy weight gain and chorioamnionitis.

American journal of human biology : the official journal of the Human Biology Council·2017
Same author

Path analysis of risk factors leading to premature birth.

American journal of human biology : the official journal of the Human Biology Council·2017

Area of Science:

  • Obstetrics and Gynecology
  • Pharmacology
  • Neonatal Medicine

Background:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like indomethacin have been used in pregnancy, but with concerns.
  • NSAIDs may affect fetal ductus arteriosus, urine production, and amniotic fluid levels.
  • Aspirin use in pregnancy is often discouraged due to bleeding and ductus arteriosus concerns.

Purpose of the Study:

  • To reexamine the use of aspirin in pregnancy.
  • To review aspirin's pharmacology and pharmacokinetics during pregnancy.
  • To assess potential risks and benefits of aspirin in pregnancy.

Main Methods:

  • Review of existing literature on aspirin's effects in pregnancy.
  • Analysis of pharmacology and pharmacokinetics relevant to pregnant individuals.
  • Evaluation of teratogenesis, bleeding risks, and effects on fetal development.

Main Results:

  • Concerns about NSAIDs, including aspirin, stem from high-dose studies and extrapolation.
  • Low-dose aspirin (60-75 mg/day) may decrease preeclampsia and intrauterine growth retardation.
  • Potential effects on fetal ductus arteriosus, bleeding, and neonatal outcomes require careful consideration.

Conclusions:

  • Revisiting aspirin's role in pregnancy is warranted due to potential benefits.
  • Balancing risks of bleeding and ductus arteriosus effects against benefits is crucial.
  • Further research is needed to fully understand aspirin's impact on pregnancy and neonates.

Related Experiment Videos