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Condition specific antepartum testing: systemic lupus erythematosus and associated serologic abnormalities.
D Adams1, M L Druzin, T Edersheim
1Department of Obstetrics and Gynecology, New York Hospital-Cornell Medical Center, New York 10021.
Summary
Antepartum fetal surveillance effectively manages pregnancies with maternal systemic lupus erythematosus. This review of "lupus pregnancies" shows a favorable perinatal mortality rate of 6.06%.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Rheumatology
Background:
- Systemic lupus erythematosus (SLE) in pregnancy requires careful management.
- Antepartum fetal surveillance is crucial for pregnancies complicated by SLE and associated serologic abnormalities.
Purpose of the Study:
- To review the experience with antepartum surveillance in "lupus pregnancies" from 1980 to 1988.
- To evaluate the perinatal outcomes in this high-risk obstetric population.
Main Methods:
- Retrospective review of antepartum surveillance data for pregnancies affected by maternal SLE.
- Analysis of perinatal mortality rates.
Main Results:
- The study reviewed pregnancies managed between 1980 and 1988.
- An overall perinatal mortality rate of 6.06% was observed.
Conclusions:
- Antepartum fetal surveillance is a key component in managing pregnancies with maternal SLE.
- The observed perinatal mortality rate is comparable to or better than previously reported ranges for SLE pregnancies.