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Related Experiment Videos

Corneal thickness at different reference points from Orbscan II system.

Andrew K C Lam1, Judy S Chan

  • 1Department of Optometry and Radiography, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.

Clinical & Experimental Optometry
|July 16, 2003
PubMed
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The thinnest corneal region is typically inferior, but its location doesn't significantly differ in thickness from the corneal apex. Orbscan II users can confidently use central reference points for corneal thickness measurements.

Area of Science:

  • Ophthalmology
  • Corneal topography
  • Ocular biomechanics

Background:

  • Corneal topography systems like Orbscan II define reference points for analysis.
  • Understanding the precise location of the thinnest corneal region is crucial for accurate assessments.
  • Investigating potential discrepancies between the corneal apex and the thinnest corneal zone is important.

Purpose of the Study:

  • To determine the location of the thinnest corneal region using the Orbscan II system.
  • To assess if there is a significant difference in corneal thickness between the corneal apex and the thinnest corneal region.
  • To evaluate the clinical significance of reference point location variations.

Main Methods:

  • Analysis of 92 eyes from 46 healthy subjects using the Orbscan II system.

Related Experiment Videos

  • Identification and categorization of three reference points: fixation point, corneal apex, and thinnest corneal region.
  • Statistical analysis to compare the location and thickness at these reference points.

    • Main Results:

    • The thinnest corneal region was predominantly located in the inferior temporal quadrant (right eye) and inferiorly (left eye).
    • No statistically significant difference was observed in corneal thickness between the thinnest region and the corneal apex.
    • A significant difference (p < 0.01) was found in the spatial location of these identified reference points.

    Conclusions:

    • While reference point locations can vary significantly, corneal thickness at the apex and thinnest point is comparable.
    • The Orbscan II system allows flexibility in choosing central reference points without compromising corneal thickness measurement accuracy.
    • These findings support the interchangeable use of central reference points for corneal thickness evaluation in clinical practice.