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Related Experiment Videos

Cortical blindness and hepatic encephalopathy.

T Ammar1, G Auzinger, G Auwzinger

  • 1King's College Hospital, Camberwell, London, UK.

Acta Ophthalmologica Scandinavica
|July 16, 2003
PubMed
Summary

This case study highlights a rare instance of permanent cortical blindness (CB) in a young man after hepatic encephalopathy. While CB usually resolves, this case shows it can persist even after treatment.

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Area of Science:

  • Neurology
  • Ophthalmology
  • Gastroenterology

Background:

  • Hepatic encephalopathy (HE) is a neuropsychiatric complication of liver dysfunction.
  • Cortical blindness (CB) is a visual impairment resulting from damage to the occipital cortex.
  • While HE-induced CB is typically reversible, persistent cases are exceptionally rare.

Observation:

  • A young man developed complete cortical blindness (CB) following hepatic encephalopathy (HE).
  • Clinical examination and investigations confirmed the diagnosis of CB.
  • The patient's condition did not improve despite treatment for HE.

Findings:

  • This case presents a previously unreported complication of permanent CB following HE.
  • The visual cortex was affected, leading to irreversible vision loss.

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  • This contrasts with the usual transient nature of CB in HE cases.
  • Implications:

    • Permanent CB is an uncommon and rarely persistent neurological sequela of hepatic encephalopathy.
    • This case underscores the potential for severe and lasting visual impairment from HE.
    • Further research into the mechanisms and management of HE-induced visual disturbances is warranted.