Related Experiment Video
Updated: Sep 23, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Selective contrast echocardiography in percutaneous transluminal septal myocardial ablation in an elderly patient
Marcelo L C Vieira1, Roderick M Silva Filho, Fábio S Brito Filho
1Division of Imaging Diagnosis, Echocardiography Laboratory Department of Cardiology Division of Imaging Diagnosis, Hemodynamic Laboratory, Hospital Israelita Albert Einstein, São Paulo, Brazil. mlcviera@aol.com
Insights
This study details a successful treatment for an elderly patient with hypertrophic cardiomyopathy. Myocardial contrast echocardiography-guided septal ablation offered an effective alternative when medical therapy failed.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Cardiology
Background:
- Hypertrophic cardiomyopathy (HCM) is a genetic heart muscle disease.
- Left ventricular concentric hypertrophy with septal thickening is a common echocardiographic finding in HCM.
- Medical management of symptomatic HCM can be challenging, with some patients showing suboptimal responses.
Observation:
- An elderly patient with hypertension and significant left ventricular hypertrophy, specifically a sigmoid septum, exhibited poor tolerance to standard medical treatments.
- The patient's condition necessitated exploring alternative therapeutic strategies.
Findings:
- Percutaneous transluminal septal myocardial ablation (PTSMA) guided by myocardial contrast echocardiography (MCE) was successfully performed.
- This minimally invasive procedure effectively addressed the patient's obstructive hypertrophic cardiomyopathy.
Implications:
- MCE-guided PTSMA represents a viable and effective treatment option for select patients with obstructive HCM who are refractory to medical therapy.
- This approach may offer improved clinical outcomes and quality of life in challenging HCM cases.
- Further research into MCE-guided interventions for HCM is warranted.
Abstract:
We report an elderly patient, with hypertension and left ventricular concentric hypertrophy with sigmoid shape of the septum, who presented an unsatisfactory response to medical treatment and who was successfully submitted to myocardial contrast echocardiography-guided percutaneous transluminal septal myocardial ablation.
Related Concept Videos
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Mitral Stenosis II: Clinical features and Diagnostic Tests

