Treatment of Fordyce spots with CO2 laser
Related Experiment Video
Updated: Sep 23, 2026
Fertility Sparing Procedure using Carbon Dioxide Fiber Laser Vaporization of Ovarian Endometrioma
Published on: July 6, 2022
Jorge Ocampo-Candiani1, Adriana Villarreal-Rodríguez, Alba G Quiñones-Fernández
1Medipiel Centros Dermatológicos, Monterrey, NL, México. jocampo2000@yahoo.com.mx
Background:
Fordyce spots are heterotopic sebaceous glands that can be located at the lips' vermilion or the oral mucosa. Although this is considered a rather common disorder, a treatment for this condition that sometimes affects patients from only a cosmetic viewpoint has not yet been described.
Objective:
To evaluate CO2 superpulsed laser treatment in two subjects with Fordyce spots.
Methods:
Two patients with papules and yellowish plaques at the upper lip corresponding to Fordyce spots were treated with coherent Ambulase CO2 superpulsed laser (Coherent Medical, Palo Alto, CA); after informed consent was obtained, two to three passes were performed in one session using 2 and 4 W and a spot size of 2 mm.
Results:
Complete re-epithelization was observed 2 weeks later with no residual Fordyce papules in the treated area and no side effects.
Conclusion:
Our findings suggest that CO2 superpulsed laser can be considered a safe and effective treatment for patients with Fordyce spots, offering excellent cosmetic results.
