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Meningioma associated with intraosseous lipoma
Yasuhiko Hayashi1, Makoto Kimura, Akira Kinoshita
1Department of Neurosurgery, Komatsu Municipal Hospital, Ho-60 Mukaimoto-ori, Ishikawa, Komatsu, Japan. yahayashi@ns.m.kanazawa-u.ac.jp
Abstract:
Intraosseous lipomas of the skull are quite rare and only eight cases have been reported. The lipoma in our case was different from that in others in that it showed remarkable proliferation of collagen tissue. This is the first report of meningioma occurring after removal of an intraosseous lipoma of the skull. This report concerns a rare case of a 32-year-old female who developed a huge convexity meningioma 11 years after successful removal of intraosseous lipoma of the left frontoparietal bone. The meningioma originated from the convexity where the lipoma had been, and extended intracranially to the sphenoid ridge. The patient underwent surgical exploration showing that the meningioma had invaded the frontoparietal convexity bone and was firmly attached to the coronal suture with a large dural defect. This rare coincidence suggests that proliferative changes of the intraosseous lipoma and meningeal neoplasm may be the result of the same, as yet unknown, mechanism.
Insights
This case report details a rare instance of a meningioma developing 11 years after skull intraosseous lipoma removal. The findings suggest a potential link between these rare bone tumors and subsequent meningioma development.
Area of Science:
- Neuro-oncology
- Skeletal Pathology
Background:
- Intraosseous lipomas of the skull are exceptionally rare, with limited documented cases.
- This report focuses on a unique case involving a skull intraosseous lipoma with significant collagen tissue proliferation.
Observation:
- A 32-year-old female presented with a large convexity meningioma 11 years post-resection of a left frontoparietal intraosseous lipoma.
- The meningioma arose from the prior lipoma site, extending intracranially to the sphenoid ridge.
- Surgical findings revealed bone invasion and adherence to the coronal suture with a dural defect.
Findings:
- This is the first reported case of meningioma following surgical removal of a skull intraosseous lipoma.
- The simultaneous occurrence suggests a possible shared underlying mechanism for both intraosseous lipoma and meningioma.
Implications:
- The findings prompt further investigation into potential common etiological factors for these rare neoplasms.
- Understanding this association may improve diagnostic and therapeutic strategies for skull base tumors.