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Generalized eczema induced by nadroparin
J L Estrada Rodriguez1, F Gozalo Reques, J Ortiz de Urbina
1Servicio de Alergia, Hospital de León, Spain. jestrada@hleo.insalud.es
Abstract:
The case of a 39-year-old female with generalized eczema following sodium nadroparin administration was referred to us. Positive patch-tests for several low molecular weight heparins (LMWH), but negative for unfractionated heparins (UFH) and tinzaparin were obtained. Furthermore, intradermal tests gave positive results to sodium and calcium heparin, while only subcutaneous challenge showed tinzaparin sensitivity. In summary, in heparin type IV hypersensitivity diagnosis, the intradermal test seems to be an eligible tool, rather than patch-test.
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