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Published on: September 15, 2023
Off-pump coronary bypass surgery and all arterial conduits: learning experience at Bangkok Heart Institute
Kitipan Visudharom1, Vibul Jotisakulratana, Vitoon Pitiguagool
1Bangkok Heart Institute, Bangkok Hospital, Bangkok 10320, Thailand.
Insights
Off-pump coronary artery bypass surgery, using all arterial grafts, offers a viable alternative to traditional bypass. This technique aims to reduce complications associated with cardiopulmonary bypass, showing promising results in a recent study.
Area of Science:
- Cardiovascular Surgery
- Minimally Invasive Cardiac Surgery
- Vascular Grafting
Background:
- Off-pump coronary artery bypass (OPCAB) surgery, performed without a heart-lung machine, has gained prominence, now accounting for approximately 25% of global coronary artery bypass procedures.
- A key objective of OPCAB is to mitigate complications linked to cardiopulmonary bypass.
- The utilization of all-arterial conduits in coronary artery bypass grafting (CABG) is increasingly accepted due to improved long-term outcomes.
Purpose of the Study:
- To evaluate the outcomes of off-pump coronary artery bypass procedures utilizing all arterial conduits.
- To assess the safety and efficacy of this technique in various patient risk groups.
Main Methods:
- A retrospective analysis of 251 off-pump coronary artery bypass procedures performed between January 2001 and December 2002.
- One hundred and nine cases specifically utilized all-arterial conduits.
- Patient data was stratified using the US National Society of Thoracic Surgeons Cardiac Surgery Database risk module into low, medium, and high-risk groups.
Main Results:
- The overall 30-day mortality rate was 3.6% (4 cases), with no peri-operative myocardial infarction or stroke.
- Patients requiring re-operation for bleeding were 3 cases, and 13 patients (14.3%) developed new atrial fibrillation.
- Minimally invasive approaches, including smaller incisions and elimination of leg incisions, facilitated faster patient mobilization and reduced post-operative pain.
Conclusions:
- Off-pump coronary artery bypass surgery with all-arterial conduits is a safe and effective procedure, particularly when employing minimally invasive techniques.
- The study highlights the benefits of reduced invasiveness, leading to improved patient recovery and reduced complications.
- This approach represents a significant advancement in coronary artery bypass grafting, offering optimal outcomes for patients.
Abstract:
Off-pump coronary artery bypass technique or bypass graft surgery without the use of a heart-lung machine has been introduced in the last six years, and now comprises approximately 25 per cent of all coronary artery bypass surgery being done in the world. One of the goals of beating heart surgery is to eliminate the complications associated with the use of cardiopulmonary bypass. The use of all arterial conduits for coronary artery bypass graft has become more acceptable after experiences gained and reports of better long-term results. From January 2001 to December 21 2002 the authors performed 251 off-pump procedures. One hundred and nine of these cases were done utilizing all arterial conduits. The data was stratified using the US National Society of Thoracic Surgeons Cardiac Surgery Database pre-operative risk module and divided into 3 groups as suggested: Low risk group with a predicted mortality of 0-1 per cent (2 patients); Medium risk group with a predicted mortality of 2-9 per cent (87 patients), and High risk group with a predicted mortality of 10+ per cent (10 patients). The predicted mortality of the entire group was 4.5 per cent. There were 90 males and 19 females with a mean age of 60.2 +/- 10.7 years, with 15.6 per cent of them older than 70 years. Pre-operative co-morbidities included 1/4 of the patients who had ejection fraction (EF) of equal to or less than 0.4, 4.5 per cent had unstable angina, 1.6 per cent had urgent/emergent status, 26.6 per cent underwent re-operative procedure, 1 per cent had pre-operative serum creatinine more than 2 mg per cent, 4.8 per cent had a history of stroke, 20.2 per cent had a history of congestive heart failure, 45.2 per cent had a history of previous myocardial infarction, 10.7 per cent had a history of chronic obstructive pulmonary disease, 46.9 per cent had a history of diabetes, 62 per cent had hypertension, and 20 patients (18.3%) required intra aortic balloon pump. Intra-operative parameters revealed 3.7 +/- 1.3 grafts/patient. The left internal mammary artery (LIMA) was used to the left anterior descending (LAD) in 6.4 per cent, or sequential with the diagonals 93.6 per cent. The 30 days mortality was 3.6 per cent (4 cases). Further analysis revealed that pre-operatively, none of these 4 cases was in the low predicted (predicted mortality of 0-1%) risk group, 2 of them were in the medium (predicted mortality of 2-9%) and the other 2 were in the high predicted risk (predicted mortality of 10+%) group. The skin-to-skin time was 4.1 hours and there were two conversions to on-pump in this group. Post-operatively, the intubation time was 4.7 hours. There was no peri-operative myocardial infarction, one patient required dialysis, and no patient experienced stroke. There was no sternal wound or arm wound infection, 9.5 per cent experienced temporal sensation impairment at the site of the radial artery harvesting at one month. Re-operation for bleeding occurred in 3 cases, and thirteen patients (14.3%) developed new atrial fibrillation. The authors are no longer making a one-foot long incision and spread ten inches wide like in the old days'. With the less invasive approach lessened in the recent past, the authors have found the less invasive the incision the less the pain after surgery. Totally eliminating the leg incision has allowed the patient to get up and mobilize on the same afternoon, if the procedure was done in the morning. All of these approaches combined with the off-pump technique, as far as the authors are concerned, will provide those who need coronary arterial bypass graft the best operative procedure.
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