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Updated: Sep 23, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
[Thrombo-embolic risk evaluation in patients with atrial fibrillation. Role of echocardiography]
S Carerj1, A Micari, S Di Rosa
1Dipartimento Clinico-Sperimentale di Medicina e Farmacologia, Università degli Studi di Messina, Messina, Italy. scipione2@interfree.it
Insights
Atrial fibrillation (AF) increases stroke risk. Transesophageal echocardiography (TEE) is crucial for detecting cardiac thrombi, enabling better risk assessment and prevention of thromboembolic events in AF patients.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Atrial fibrillation (AF) is the most common cardiac arrhythmia.
- AF is a primary cause of thromboembolic events, often originating from the left atrium or appendage.
- Identifying high-risk patients is crucial for effective therapy and stroke prevention.
Purpose of the Study:
- To evaluate the role of echocardiography in assessing thromboembolic risk in patients with AF.
- To compare the diagnostic capabilities of Transthoracic Echocardiography (TTE) and Transesophageal Echocardiography (TEE) for thrombus detection.
Main Methods:
- Review of clinical, laboratory, and echocardiographic data for risk stratification.
- Comparison of Transthoracic Echocardiography (TTE) sensitivity (33-72%) versus Transesophageal Echocardiography (TEE) sensitivity (nearly 100%) for thrombus detection.
Main Results:
- Transthoracic echocardiography (TTE) has limited sensitivity for detecting thrombi in posterior cardiac structures.
- Transesophageal echocardiography (TEE) demonstrates high sensitivity (nearly 100%) in identifying cardiac thrombi.
- Combined echocardiographic and clinical data improve risk stratification for thromboembolism.
Conclusions:
- Transesophageal echocardiography (TEE) is essential for accurate thrombus detection in AF patients.
- TEE is mandatory for effective thromboembolism prevention strategies in atrial fibrillation.
- Multimodal risk stratification using TEE and clinical data optimizes patient management.
Abstract:
Atrial fibrillation (AF) is the most common observed cardiac arrhythmia and is the most frequent condition associated with thromboembolic events in patients with or without mitral valve disease. The source of cardiac emboli is the left atrium, the left atrial appendage or, less frequently, the left ventricle. Emboli may also originate from aortic atherosclerotic plaques. It is important to identify patients at risk in order to perform the appropriate therapy. Risk stratification is multiparametric, being based on clinical, laboratory, and echocardiographic data. Several trials have pointed out the role of echocardiography in the evaluation of anatomic and functional parameters associated with thromboembolic risk. Transthoracic echocardiography (TTE) does not provide sufficient information regarding posterior cardiac structures, being its sensitivity in detecting thrombi relatively low (33-72%). Transesophageal echocardiography (TEE) in contrast, has an almost 100% sensitivity; this technique is, therefore, mandatory in patients with AF for an adequate prevention of thromboembolism. The echocardiographic information joined with clinical features allow to stratify, in a proper way, the risk of every single patient.
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