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Related Concept Videos

Hearing01:31

Hearing

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When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
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Preventive Healthcare Services01:30

Preventive Healthcare Services

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Unrenewable Cells00:50

Unrenewable Cells

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In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of...
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Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
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Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
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Anatomy of the Ear01:16

Anatomy of the Ear

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Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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[Laryngeal involvements in systemic diseases : a discussion based on a case report.]

Revue medicale de Liege·2017
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[CSF otorrhea: case report and management].

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Connectivity graph analysis of the auditory resting state network in tinnitus.

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[Regeneration of hair cells and auditory neurons in the ear].

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Related Experiment Video

Updated: Mar 8, 2026

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages
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Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

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[Prevention of deafness].

Ph Lefèbvre1

  • 1Service d'Oto-rhinolaryngologie, Centre de Recherches en Neurobiologie Cellulaire et Moléculaire (CNM), Université de Liège. PP.Lefebvre@ulg.ac.be

Revue Medicale De Liege
|July 19, 2003
PubMed
Summary

Deafness, affecting 17% of the population, often results from hair cell and neuron degeneration. This review covers drug-induced (aminoglycosides, platin) and sound trauma-induced hearing loss, exploring protective strategies and therapeutic developments.

Area of Science:

  • Ototoxicology
  • Neuroscience
  • Audiology

Context:

  • Hearing loss affects approximately 17% of the global population.
  • Inner ear damage, including hair cell and auditory neuron degeneration, is a primary cause of deafness.
  • Environmental factors significantly contribute to the development of hearing loss.

Purpose:

  • To review major causes of deafness: drug-induced and sound trauma-induced hearing loss.
  • To explore protective strategies and therapeutic interventions for preventing inner ear damage.
  • To discuss the pathophysiology of ototoxicity and sound-induced damage.

Summary:

  • Aminoglycosides and platin derivatives are ototoxic, causing hair cell and auditory neuron death.
  • Understanding ototoxicity mechanisms has led to new therapeutic strategies for inner ear protection.

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Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
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  • Sound trauma, often occupational, necessitates collective, individual, and informational prevention measures.
  • Novel drugs for preventing hearing loss are under development.

    • Impact:

    • Provides insights into preventing neurosensory structure degeneration in the inner ear.
    • Highlights the importance of environmental modification for hearing preservation.
    • Informs the development of new treatments and preventative measures against hearing loss.