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Updated: Sep 23, 2026

Examining the Conformational Dynamics of Membrane Proteins in situ with Site-directed Fluorescence Labeling
Published on: May 29, 2011
Development of fluorescent sensing of anions under excited-state intermolecular proton transfer signaling mechanism
Xuan Zhang1, Lin Guo, Fang-Ying Wu
1Department of Chemistry and the MOE Key Laboratory of Analytical Sciences, Xiamen University, Xiamen 361005, China.
Abstract:
[reaction: see text] A substantially red-shifted fluorescence emission in 3-hydroxyl-2-naphthanilide in acetonitrile was developed and drastically enhanced upon addition of anions such as F(-), AcO(-), and H(2)PO(4)(-), with the enhancement depending on anion basicity. Excited-state intermolecular proton transfer in the sensor-anion hydrogen-bonding complex was suggested to be the signaling mechanism.
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