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Updated: Sep 23, 2026

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
Published on: August 30, 2019
Can inflammatory mediators affect fibrinolysis in the pleural space?
1The University of Texas Health Center at Tyler (UTHCT), 11937 US Highway 271, Tyler, TX 75708-3154, USA.
Abstract:
The pleural space in patients with empyema and complicated parapneumonic effusions is a stage for intensive activity representing mobilization of various host responses. Release of inflammatory mediators accompanied by influx of leucocytes as well as alternations of the fibrinolytic cascade are some of the characteristic events occurring in the pleural space during infection. The possible relationship between these two systems is the subject of the article by Alemán and co-workers in this issue of Clinical Science, and is discussed in this comment.
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