Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Erdheim-Chester disease.

Kimble M Opie¹, Joey Kaye, Carl Vinciullo

¹Department of Dermatology, Royal Perth Hospital, Perth, Western Australia, Australia.

The Australasian Journal of Dermatology

|July 19, 2003

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Six months of hybrid closed-loop therapy improves diabetes-specific positive well-being, and reduces diabetes distress and fear of hypoglycemia: secondary analysis of a randomized controlled trial.

BMJ open diabetes research & care·2025

Same author

Results of an Australian trial of an automated insulin delivery (AID) system and other studies support likely benefit of AID use for many Australian adults with type 1 diabetes.

Internal medicine journal·2024

Same author

Driving with Type 1 Diabetes: Real-World Evidence to Support Starting Glucose Level and Frequency of Monitoring During Journeys.

Diabetes technology & therapeutics·2022

Same author

Repair of Two Nasal Defects.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2021

Same author

Meal-time glycaemia in adults with type 1 diabetes using multiple daily injections vs insulin pump therapy following carbohydrate-counting education and bolus calculator provision.

Diabetes research and clinical practice·2021

Same author

Three- Versus Seven-Day Tie-Over Bolsters for Full Thickness Skin Grafts on the Nose, Results of a Prospective Comparative Nonrandomized Blinded Clinical Trial.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2021

Erdheim-Chester disease, a rare non-Langerhans cell histiocytosis, can manifest as numerous dermal nodules. This case highlights the diverse cutaneous presentations of Erdheim-Chester disease (ECD).

Area of Science:

Dermatology
Pathology
Oncology

Background:

Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis.
It is characterized by lipid-laden macrophages infiltrating various organs.
Cutaneous manifestations are not widely recognized but can be significant.

Observation:

A 38-year-old male presented with numerous dermal nodules.
These nodules were histologically consistent with Erdheim-Chester disease.
Other observed cutaneous signs included xanthelasma, pretibial dermopathy, and mucosal lesions.

Findings:

Histological confirmation of Erdheim-Chester disease was established.
The diagnosis was initially made on retroperitoneal tissue.
Pathognomonic long bone X-ray findings confirmed the diagnosis.

Related Experiment Videos

Implications:

This case expands the understanding of Erdheim-Chester disease's varied clinical presentations.
Recognizing cutaneous signs can aid in earlier diagnosis of ECD.
Further research into ECD's dermatological aspects is warranted.